Athaya Febriantyo Purnomo, Nurul Cholifah Lutfiana, Adilla Shafryantyo Purnomo, Azzahra Syadza Nasywantya Purnomo, Ilham Satriawan, R. Mohamad Javier
Background: Chronic Kidney Disease (CKD) has become a significant global health issue, especially among the aging population. Renal transplantation is considered the most effective treatment for end-stage renal disease (ESRD), yet disparities exist in its accessibility and outcomes across different regions. Objectives: This study aimed to compare the perspectives and outcomes of renal transplantation in adult and geriatric patients with CKD in Europe and Indonesia, highlighting differences in healthcare systems, patient management, and socio-cultural considerations. Methods: A literature review was conducted using PubMed, ScienceDirect, and Google Scholar, focusing on publications from the last 10 years. Studies involving adult and elderly CKD patients undergoing renal transplantation in both Europe and Indonesia were analyzed for themes related to access, outcomes, quality of life, and post-transplant management. Results: European countries generally demonstrated more structured transplantation programs, better post-operative care, and higher graft survival rates due to strong infrastructure and funding. In contrast, Indonesian patients faced challenges such as limited donor availability, economic constraints, and lower awareness about transplantation. Geriatric patients in both regions exhibited more complications post-transplantation compared to younger adults, but still benefited in terms of survival and quality of life. Discussion: Disparities between Europe and Indonesia in renal transplantation stem from differences in healthcare access, government support, and patient education. Cultural and ethical issues also influence organ donation rates. Despite challenges, renal transplantation remains a viable option for geriatric patients, especially with proper selection and monitoring. Conclusion: While renal transplantation offers improved outcomes for CKD patients globally, substantial disparities remain between regions. Efforts to enhance transplantation programs in developing countries like Indonesia are crucial, especially in addressing the needs of the aging population. © 2025 Athaya Febriantyo Purnomo, Nurul Cholifah Lutfiana, Adilla Shafryantyo Purnomo, Azzahra Syadza Nasywantya Purnomo, Ilham Satriawan, R. Mohamad Javier This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/./) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Department of Urology, Faculty of Medicine, Universitas Brawijaya, Saiful Anwar General Hospital, East Java, Malang, Indonesia; Department of Biomedicine and Biochemistry, Faculty of Medicine, Universitas Muhammadiyah Surabaya, East Java, Surabaya, Indonesia; Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Brawijaya, Saiful Anwar General Hospital, East Java, Malang, Indonesia; Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia; Faculty of Medicine, Universitas Brawijaya, East Java, Malang, Indonesia; Department of Cardiovascular, Universitas Indonesia Hospital, Jakarta, Indonesia
