Rimayanti Rimayanti, Aswin Rafif Khairullah, Suzanita Utama, Riza Zainuddin Ahmad, Sri Mulyati, Ratna Damayanti, Tita Damayanti Lestari, Imam Mustofa, Tatik Hernawati, Wasito Wasito, Ikechukwu Benjamin Moses, Bantari Wisynu Kusuma Wardhani, Dea Anita Ariani Kurniasih, Shelly Kusumarini, Syahputra Wibowo, Sheila Marty Yanestria, Muhammad Khaliim Jati Kusala, Ertika Fitri Lisnanti, Ima Fauziah
The protozoan parasite Neospora caninum is a cause of infectious disease neosporosis. Neospora caninum is a major parasite affecting dogs and livestock worldwide. Neosporosis is a major cause of abortion in cattle, particularly in cattle raised in intensive agriculture. For diagnosis, the indirect enzyme-linked immunosorbent assay and immunofluorescence antibody test are employed. Neospora caninum goes through three different stages in its life cycle: sporozoites, tachyzoite, and bradyzoite. The primary method of N. caninum transmission in cattle is believed to be transplacental. Dogs are the definitive hosts of N. caninum, and the organisms in dogs and cattle are indistinguishable from one another. A high prevalence of N. caninum infection in animals was linked to the presence of dogs that tested positive for the parasite. Although exact statistics on the financial losses resulting from neosporosis in the global livestock sector are unavailable, losses are estimated to be millions of dollars. A number of medications have been investigated against N. caninum. In infected cell cultures, piritrexim, monensin, pyrimethamine, and trimethoprim stop N. caninum from growing intracellularly. Taking action to stop vertical transmission is the most practical way to control neosporosis in cattle herds, considering the current state of knowledge. © 2025, Faculty of Veterinary Medicine, University of Tripoli. All rights reserved.
Division of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia; Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia; Division of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia; Department of Applied Microbiology, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria; Research Center for Pharmaceutical Ingredients and Traditional Medicine, National Research and Innovation Agency (BRIN), Bogor, Indonesia; Research Center for Public Health and Nutrition, National Research and Innovation Agency (BRIN), Bogor, Indonesia; Department of Veterinary Parasitology, Faculty of Veterinary Medicine, Universitas Brawijaya, Malang, Indonesia; Eijkman Research Center for Molecular Biology, National Research and Innovation Agency (BRIN), Bogor, Indonesia; Faculty of Veterinary Medicine, Universitas Wijaya Kusuma Surabaya, Surabaya, Indonesia; Program of Animal Husbandry, Faculty of Agriculture, Universitas Islam Kadiri, Kediri, Indonesia
