Sri Rahayu, Sri Widyarti, Aris Soewondo, Dian Islami Prasetyaningrum, Umarudin Umarudin, Mochammad Fitri Atho’illah
The aim of the present work is to obtain Ocimum africanum extract nanoparticles (OaE-NPs) that have been crosslinked via ionic gelation with chitosan (chi) and sodium tripolyphosphate (TPP). Nanoencapsulation will enable investigation of the morphology profile and size of OaE-NPs. The OaE-NPs produced via ionic gelation exhibited a 6.4 nm in size and a low polydispersity index (PDI) of 0.177. Additionally, SEM observation revealed that the surface shape of OaE-NPs was a loose aggregate with an uneven surface. These findings provide a simple and reliable approach for generating nanoparticles from O. africanum coated with chitosan/TPP. © The Authors, published by EDP Sciences.
Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, East Java, Malang, Indonesia; Department of Socio-Economic Agriculture, Faculty of Agriculture, Brawijaya University, East Java, Malang, 65145, Indonesia; Program Study of Pharmacy, Pharmacy Academy of Surabaya, East Java, Surabaya, 60232, Indonesia; Doctoral Program of Biology, Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, East Java, Malang, Indonesia
