Ceruminous Gland Tumors in Canines and Felines: A Scoping Review

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Tiruvilvamala Ramesh Lavanya, Pavan Kumar, Mun Keong Kok, Siew Mei Ong, Rozanaliza Radzi, Gayathri Thevi Selvarajah

2025 Animals Vol. 15 Issue 8 Review Cited by 1 Quartile

Abstract

Ceruminous glands are specialized apocrine sweat glands. Neoplastic transformation of these glands is often seen in the external ear canal. Tumors arising from these glands can present a diagnostic dilemma because of their varied clinical and histological manifestations. This study was conducted as little information is currently available on these neoplasms. The present study undertakes a scoping review of research on canine and feline CGTs according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines for scoping reviews on three databases (NCBI-PubMed, Scopus and ScienceDirect) from 1980 to 2023 (43 years) to determine the extent of the existing literature on its clinicopathological characteristics, overall prognosis, survival rates, and biomarker studies. Seventeen canine and nineteen feline publications that met the inclusion criteria were analyzed. Eleven canine and twelve feline unpublished cases of CGTs managed in Malaysia were also reviewed. Our study concluded surgical excision as part of the treatment for this neoplasia may lengthen animals’ survival period and produce a satisfactory quality of life; however, a substantial risk of complications, especially after aggressive surgical excision, exists. © 2025 by the authors.

Affiliations

Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Serdang, 43400 UPM, Malaysia; University Veterinary Hospital, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Serdang, 43400 UPM, Malaysia; Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, Selangor, Serdang, 43400 UPM, Malaysia; College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Punjab, Ludhiana, 141004, India; CanRes MAKNA Laboratory, Institute of Bioscience, Universiti Putra Malaysia, Selangor, Serdang, 43400 UPM, Malaysia; Faculty of Veterinary Medicine, Universitas Brawijaya, East Java, Malang, 65146, Indonesia