Bioactive Compounds and Chemodiversity in Tropical Brown Macroalgae: Insights from Padina, Sargassum, and Turbinaria

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Safri Ishmayana, Mostefa Fodil, Danang A. Prabowo, Diah R. Noerdjito, Debora C. Purbani, Varian Fahmi, Wiwin Natalia, Ronny Lesmana, Mochamad F. A. Ismail, Ankiq Taofiqurohman, Ibnu Faizal, Muhammad Yusuf, Sulastri Arsad, Nia Rossiana, Jean-Luc Mouget, Fiddy S. Prasetiya

2025 Egyptian Journal of Aquatic Biology and Fisheries Vol. 29 Issue 2 Article Cited by 0 Quartile

Abstract

Despite the extensive efforts made to isolate and identify novel compounds with potential medicinal, health, or pharmaceutical applications, very few compounds are available to use with real potency. Seaweeds are macroscopic and multicellular marine algae that provide essential sources of bioactive metabolites in the health, pharmaceutical, and other industries. Bioactive compounds from seaweeds include sulfated polysaccharides, phlorotannins, and diterpenes. These compounds have been reported with profound anti-viral, anti-proliferative, and anti-cancer properties. The present mini review elaborates on the pharmaceutical, health, and research potentials of different bioactive compounds produced by the tropical brown seaweeds (Phaeophyta) from the genera Padina, Sargassum, and Turbinaria. © 2025, Egyptian Society for the Development of Fisheries and Human Health. All rights reserved.

Affiliations

Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Indonesia; Laboratoire Biologie des Organismes Stress Santé Environnement (BiOSSE), Le Mans Université, France; Research Center for Biosystematics and Evolution, Research Organization for Life Sciences and Environment, National Research and Innovation Agency (BRIN), Indonesia; Research Center of Biotechnology and Bioinformatics, Universitas Padjadjaran, Indonesia; Physiology Division, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Indonesia; Division of Biological Activity, Central Laboratory, Universitas Padjadjaran, Sumedang, Indonesia; Center of Excellence in Higher Education for Pharmaceutical Care Innovation, Universitas Padjadjaran, Indonesia; Research Center for Climate and Atmospheric Study (PRIMA), Research Organization of Earth and Maritime, National Research and Innovation Agency (BRIN), Indonesia; Department of Marine Sciences, Faculty of Fisheries and Marine Sciences, Universitas Padjadjaran, Indonesia; Study Program of Aquatic Resources Management, Faculty of Fisheries and Marine Science, Universitas Brawijaya, Malang, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang, Indonesia