Andreas Bandang Hardian, Syavira Ekdhiasmara, Saputra Jaka Prayoga, Nur Fitri Destriani, Tessa Saputri Marmanto, Eka Nur Prasetyawati, Pradhana Kurniawan Cadiwirya, Gamma Prajnia, Roosy Margaretha Riupassa, Winda Syafitri, Aneke Putri Yulie Dhayanti, Eko Budiarto, Galuh Herin Faranisa, Chiara Palmieri
Background: Understanding the case proportion of neoplastic and non-neoplastic disease in companion animals could reveal the trends; novel subtypes architectures, differential diagnoses and disease prognoses based on histopathological features for clinical purposes and future epidemiological study. This study aimed to explore trends, patterns, histopathological features and potential paraneoplastic syndromes associated with tumors in companion animals. Methods: Archived neoplastic tissue samples were collected over five years from an animal hospital, clinics, and veterinary practitioners in Malang Raya, Indonesia and processed through routine histopathologic examination. Results: A minimum of 30 feline and 40 canine patients with confirmed neoplastic lesions were identified, with glandular tumors being the most frequently reported in both species. Twenty-four non-neoplastic superficial masses were also reported including subcutaneous abscess, granulomatous dermatitis, pseudomycetoma/deep fungal mycosis, and panniculitis. Different regions worldwide may show varying prevalence rates and distinct patterns in the most frequently encountered abnormal superficial masses. Conclusions: Understanding these trends and considering the potential differential diagnoses can assist diagnosticians in systematically ruling out less likely conditions. The significant/notable proportion of neoplastic cases in companion animals underscores the importance of further investigations into possible environmental carcinogens, which may also pose risks to human health. © 2025, University of the Philippines at Los Banos. All rights reserved.
Laboratory of Veterinary Anatomic Pathology, Faculty of Veterinary Medicine, Universitas Brawijaya, Jl. Puncak Dieng, Kunci, Kalisongo, Dau, East Java, Malang, 65151, Indonesia; Brawijaya Academic Animal Hospital, Universitas Brawijaya, Jl. Puncak Dieng, Kunci, Kalisongo, Dau, East Java, Malang, 65151, Indonesia; Bachelor Student of Faculty of Veterinary Medicine, Universitas Brawijaya, Jl. Puncak Dieng, Kunci, Kalisongo, Dau, East Java, Malang, 65151, Indonesia; Malang Animal Care, Ruko Ditas, Jl. MT. Haryono No. Kav. 16, Dinoyo, Lowokwaru, East Java, Malang, City, 65145, Indonesia; Luna Pethouse, Jl. Sunan Kalijaga No.1, Dinoyo, Lowokwaru, East Java, Malang City, 65149, Indonesia; Panthera Vet, Jl. Candi Sari II No.3, Mojolangu, Kec. Lowokwaru, East Java, Malang City, 65142, Indonesia; Okami Animal Clinic, Jl. Sudimoro No.10 A, Mojolangu, Lowokwaru, East Java, Malang City, 65142, Indonesia; Winadivet Petcare, l. Laksda Adi Sucipto No.221, Blimbing, Blimbing, East Java, Malang City, 65126, Indonesia; Pet House Drh, Jl. Agus Salim No.87, Sisir, Batu, East Java, Batu City, 65311, Indonesia; School of Veterinary Science, Faculty of Science, The University of Queensland, Australia
