Sri Budhi Rianawati, Wahyuni Ramadhani Suaib
Introduction: Tuberculous meningitis is a form of extrapulmonary tuberculosis (TB) characterized by subacute or chronic inflammation of the meninges due to invasion of the subarachnoid space by Mycobacterium tuberculosis bacilli. Tuberculous meningitis affects about 100,000 people annually worldwide. Cognitive impairment can occur in tuberculous meningitis. Cognitive impairment has been reported as a common complication of adult tuberculous meningitis, but few studies have systematically assessed the frequency and nature of the disorder. Case series: There were two cases regarding mild cognitive impairment caused by tuberculous meningoencephalitis. The first case occurred in a woman, 40 years old, who complained that she often forgot and often daydreamed. The second case, a woman, 25 years old, who complained that she sometimes forgot and find it difficult to tell the time and numbers. In both cases, a cognitive examination was carried out, and the results of the cognitive examination gave results of cognitive impairment caused by inflammation caused by TB. Conclusion: Both patients in this case experienced mild cognitive impairment caused by tuberculous meningitis. Therefore, prompt diagnosis and therapy are necessary to increase quality of life, reduce high mortality and severe sequelae. WHO recommends between 9-12 months of treatment is sufficient to successfully treat tuberculous meningitis. © 2025 Universiti Putra Malaysia Press. All rights reserved.
Department of Neurology, Faculty of Medicine, Brawijaya University, Jawa Timur, Malang, 65145, Indonesia
