Herna Febrianty Sianipar, Rezi Rahmi Amolia, Wahyu Widoretno, Luchman Hakim, Fatchiyah Fatchiyah
Bioactive compounds are important components that the Tapanuli orangutan (Pongo tapanuliensis) needs to maintain its health. It is important to know the specific bioactive components contained in the fruit that Tapanuli orangutans eat and the effective solvents to provide up-to-date information about the content of the fruit they eat. This research uses the maceration method with ethanol and methanol solvents to determine the solvent that produces larger extracts as well as liquid chromatography-mass spectrum to analyze the bioactive component profiles of five types of fruit eaten by Tapanuli orangutans from Camp Mayang, North Sumatra. The research results showed that the ethanol solvent produced greater extracts and the five types of fruit were dominated by bioactive compounds dissolved in ethanol. The results of LC-MS/MS analysis of the ethanol extract showed that the specific bioactives that dominate the fruit eaten by Tapanuli orangutans are Campnosperma auriculatum, namely Triterpenoid (Oleanonic Acid), Agathis borneensis, namely Terpenoid (Cinerin I), Artocarpus heterophyllus, namely Steroid (Nandrolone), Castanopsis argantea, namely Terpenoid (Semiplenamide). A), and Aglaia tomentosa, namely Triterpenoids (Methyl Angolensate). The results showed that the five samples contained specific biological components that the Tapanuli orangutan could use as medicine © 2025 The Authors, published by EDP Sciences.
Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, Malang, 65145, Indonesia; Yayasan Ekosistem Lestari, Medan, 20131, Indonesia; Universitas HKBP Nommensen Pematangsiantar, Pematangsiantar, Indonesia; Research Center of Smart Molecule of Natural Genetics Resources, Brawijaya University, Malang, 65145, Indonesia
