Solvent effect on morphology of polystyrene coating and their role to improvement for biomolecule immobilization in application of QCM based biosensor

Open

Masruroh, D.J.D.H. Djoko, Lalu A. Didik, Eka Rahmawati, Masdiana Pagaga, Abdurrouf, S.P. Sakti

2014 Applied Mechanics and Materials Vol. 530-531 Conference paper Cited by 8 SDG 14SDG 12SDG 9SDG 17 Quartile

Abstract

This research is focused on the synthesis of a polystiren layer for biosensors based on a Quartz Crystal Microbalance sensor (QCM) to immobilize the biomolecule. The polystyrene thin film was deposited by means of spin coating method with various solvents, such as chloroform, toluene, xylene, and tetrahydrofuran (THF), containing a 3% polystyrene solution by mass. The morphologies of the polystyrene layers were observed via SEM/EDx. The polystyrene surface coated using chloroform as the solvent has a rougher morphology and the largest diameter pores compared with the other solvents. The result show the polystyrene surface coating produced with chloroform caused a higher frequency change, which resulted in the binding of a wider range of biomolecules. © (2014) Trans Tech Publications, Switzerland.

Affiliations

Department of Physics, Brawijaya University, Malang 65145, Indonesia; Collaborative Research Group for Advanced System and Material Technology (ASMAT), Brawijaya University, Malang, Indonesia; Graduate School Department of Physics, Brawijaya University, Malang 65145, Indonesia; Department of Veterinary Medicine, Brawijaya University, Malang, 65145, Indonesia

Research at a Glance

Premium content — register to unlock

Research at a Glance

Register to unlock

Topics & SDG Alignment

Premium content — register to unlock

Topics & SDG Alignment

Register to unlock

Collaboration

Premium content — register to unlock

Collaboration

Register to unlock

Author Profile (Selected)

Premium content — register to unlock

Author Profile (Selected)

Register to unlock

References Overview

Premium content — register to unlock

References Overview

Register to unlock

Journal & Source

Premium content — register to unlock

Journal & Source

Register to unlock

Metadata & Integrity

Premium content — register to unlock

Metadata & Integrity

Register to unlock