Lady Cindy Soewarlan, Eddy Suprayitno, Hardoko, Happy Nursyam
This study was aimed at knowing the ability of A typica to damage the stomach tissues. Method used in the study was an abservational design. Rats were divided into risk group and non-risk group (control). The former was orally infected with stadium-3 (L3) larvae of A typica and the latter was not infected. After infection of 2-8 hours, observations were carried out on both groups for larva occurrence in the stomach. The stomach tissues, where larvae were found, were preserved for histopathological analysis using Hematocylineosin (HE) staining. Stomach tissue defect analysis used 4 histopatholical lesions: epithelial exfoliation, hyperemia / hemorrhage, inflammation and amount of mucous cap cells. The histopathological analysis showed that there was no inflammation in control group but there were moderate to severe inflammation in the risk one. Acute inflammation is indicated with mucosal erosion and ulceration and the presence of polymorphonuclear cells (PMN) in the risk group. © 2015, Sphinx Knowledge House. All Right reserved.
Brawijaya University, Malang, Indonesia; Nusa Cendana University, Kupang, Indonesia
