Is cinnamaldehyde have an effect as immunostimulator ?

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Dahliatul Qosimah, Sri Murwani, Muhaimin Rifa’I, Risky Fajar Meirawan, Riski Arya Pradikta, Indah Amalia Amri, Putri Akte, P. Dian Anggraini, A. Firmansyah, Muh Mashuri

2016 International Journal of ChemTech Research Vol. 9 Issue 5 Article Cited by 0 Quartile

Abstract

The aim of this research is to know the role of cynnamaldehyde contained in the cinnamon ethanol extract as immunostimulator against Salmonella enteridis. Cynnamaldehyde could improve immune system but until now the research about that has not been widely reported. The research used Completely randomized design which consists of 6 groups in curative treatment divided into 4 groups of Balb-c mice infected with amount of bacteria 0, 25x108 cfu/ml administered orally with cynnamaldehyde in different doses were 50, 100, 150, 200 mg/ml consecutively, negative control given no bacteria and positive control only given bacteria. The cynnamaldehyde didn’t impact to the expression of CD4, CD8, CD62L T lymphocyte and B220IgD, it means that cynnamaldehide has no effect as immunostimulator. © 2016, Sphinx Knowledge House. All Rights Reserved.

Affiliations

Laboratorium of Microbiology and Immunology, Brawijaya University, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, Indonesia; Indonesia Maju School of Public Health, Indonesia