Acute adrenal insufficiency as the primary manifestation of extrapulmonary tuberculosis: A case report

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Herman Trianto, Nurria Betty, Laksmi Sasiarini, Rulli Rosandi, Putu Arsana, Djoko Soeatmadji, Achmad Rudijanto

2016 Journal of the ASEAN Federation of Endocrine Societies Vol. 31 Issue 1 Article Cited by 0 Quartile

Abstract

Acute adrenal insufficiency (AI) is a life-threatening condition. While Addison’s disease (AD) is rare, in developing countries, tuberculosis (TB) still remains as the primary cause in 7 to 20% of cases. Urinary TB is also the third most common form of extrapulmonary disease. We report a case of 37-year-old male who presented with weakness, anorexia, weight loss, dysuria, flank pain and low grade fever. Examination revealed hypotension, hyperpigmentation, hyponatremia, hypoglycemia and low serum cortisol. He was diagnosed to have adrenal crisis due to Addison’s disease and extrapulmonary TB manifesting as urinary tract infection (UTI). He was treated with corticosteroids and anti-TB medications. Urologic reconstructive surgery was subsequently planned. © 2016 by the JAFES.

Affiliations

Metabolic Disease and Diabetes Division, Internal Medicine Department Brawijaya University - Saiful Anwar General Hospital, Malang, Indonesia