Prasetyadi Mawardi, Handono Kalim, Kusworini Handono Kalim, Loeki Enggar Fitri, Karyono Mintaroem, Ambar Mudigdo, Oyong, Brian Wasita
Objective To study the aggressiveness of basal cell carcinoma (BCC) on the mid-face location. Methods A total of 30 patients were diagnosed using specimen biopsy with hematoxylin-eosin stain at Moewardi Public Hospital in Surakarta, Central Java, Indonesia. The age, gender distribution, site of the lesion, as well as clinic-pathological appearance were analyzed. Results There were 30 patients consisting of 46.7% males and 53.3% females with ages ranging from 33 to 91 years old and with the most common occupation, such as farmers (53.6%) and housewives (26.7%). Morpheaform subtypes BCC were more frequent than other types. Based on the predilection, most of the BCC were found to be in the mid-face (76.7%) and using determined criteria of histopathological examination, the aggressive appearance was 77% and non-aggressive BCC was 23%. The BCC on the mid-face location was more aggressive than the other sites (P < 0.05). Conclusions BCC is the most common skin tumor in humans with rare metastases, which might cause significant damage due to its local recurrences and aggressiveness. BCC on the mid-face is significantly more aggressive than that on the other predilection sites. © 2016 Asian Pacific Tropical Medicine Press
Dermatovenereology Department, Medical Faculty, Sebelas Maret University, Surakarta, Central Java, Indonesia; Dermatovenereology Department, Moewardi Public Hospital, Surakarta, Central Java, Indonesia; Internal Medicine Department, Faculty of Medicine, University of Brawijaya, Malang, East Java, Indonesia; Saiful Anwar Public Hospital, Malang, East Java, Indonesia; Clinical Pathology Department, Faculty of Medicine, University of Brawijaya, Malang, East Java, Indonesia; Parasitology Department, Faculty of Medicine, University of Brawijaya, Malang, East Java, Indonesia; Pathology Department, Faculty of Medicine, University of Brawijaya, Malang, East Java, Indonesia; Pathology Department, Medical Faculty, Sebelas Maret University, Surakarta, Central Java, Indonesia
