Agustin Iskandar, Muhammad Rasjad Indra, Satuman, Novi Khila Firani, Titin Andri Wihastuti
Objective: To find out the levels of Toxoplasma gondii (T. gondii) profilin and adiponectin in obese patients complicated with or without metabolic syndrome as compared to non-obese patients. Methods: This study was an observational analytic study using cross sectional design. After interview, the subjects were performed with a anthropometric test and then a metabolic syndrome panel. The levels of profilin and adiponectin were detected by using ELISA method. Results: There was a significant difference of T. gondii profilin between the obese complicated with metabolic syndrome group and the non-obese group (P = 0.00; α = 0.05), as well as the metabolically healthy obese, in which the level of profilin was significantly higher in the group as compared to the non-obese group (P = 0.001; α = 0.05). Adiponectin level of the obese complicated with metabolic syndrome group was significantly lower as compared to the metabolically healthy obese and non-obese group (P = 0.001; α = 0.05). Conclusions: The level of T. gondii profilin in obese patients was higher than that in the non-obese, whereas the level of adiponectin in obese patients complicated with metabolic syndrome was lower than that in the obese without metabolic syndrome and non-obese patients. © 2016 Asian Pacific Tropical Medicine Press.
Department of Parasitology, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia; Department of Physiology, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia; Department of Biochemistry, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia; Department of Nursing, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia
