An observation of histological evidence on internal organ damages in mice caused by repeated exposures to motorcycle emissions

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Arinto Y.P. Wardoyo, Unggul P. Juswono, Johan A.E. Noor

2017 AIP Conference Proceedings Vol. 1844 Conference paper Cited by 4 Quartile

Abstract

Motor vehicle emissions have been identified as a source of ultrafine particles, which have significant impacts on human health. Repeated and prolonged exposure to ultrafine particles may have a significant association with organ damage. Here, we evaluated the correlation between repeated exposure to ultrafine particles and organ damage in mice. Motorcycle emissions were injected into an exposure chamber with mice for a period of 20 seconds. This treatment was conducted over 10 days. The mice were sacrificed on the 2nd, 4th, 6th, 8th, and 10th days for organ preparations. Based on the results, motorcycle emission exposure caused organ damage in mice, with different severities depending on the organ. The highest damage was found for the lung, followed by the kidney, erythrocytes, and liver. © 2017 Author(s).

Affiliations

Physic Department, Brawijaya University, Jalan Veteran, Malang, Indonesia