Anny Sulistiyowati, Ria Indriyanie
Background Patients with Diabetes Mellitus (DM) often experience blurred vision due to changes in blood glucose levels. This may be caused by alterations in the refractive system, retina, optic nerve or brain disorders. The purpose of this research was to determine which biometric parameters (central corneal thickness/corneal curvature/lens thickness) have the dominant influence on refractive status caused by changes in blood glucose levels in people with diabetes mellitus during hyperglycemia and normoglycemia. Methods This research was an observational analytic study of pre- and post-test design. The subjects were newly diagnosed type 2 DM patients with Internal Disease Polyclinic aged 40-50 years old. Variables measured include CCT, corneal curvature, lens thickness, refractive status when hyperglycemic and normoglycaemic (four weeks after treatment). There were 11 respondents, consisting of two men and nine women. Results There were significant differences between CCT, corneal curvature, lens thickness and visual acuity at the time of hyperglycemia and normoglycemia (p < 0.005). Regression analysis showed that CCT, corneal curvature, and lens thickness do not have a dominant role on refractive status (p > 0.005), but corneal curvature has the dominant role on visual acuity when hyperglycemia occurs. Conclusion Biometric parameters (CCT, corneal curvature, and lens thickness) do not have any dominant influence on refraction status in the presence of changes in blood glucose levels, but cornea curvature has a significant effect on vision when hyperglycemia occurs. The thickness of central cornea, corneal curvature, and lens thickness are significantly affected by changes in blood glucose levels. © 2018 Wolters Kluwer Medknow Publications. All rights reserved.
Department of Ophthalmology, Brawijaya University/Saiful Anwar General Hospital, Malang, Indonesia
