Purnomo, Putu Hadi Setyarini, Ana Hidayati Mukaromah
Silk fibroin is an outstanding material because of their biocompatible and excellent mechanical properties. This review article is focused on silk fibroin and silk fibroin-based composites that are used as biomaterials and their potential for composite reinforcing materials for artificial bone engineering. This material is chosen because it is biocompatible, low biodegradable, as well as ease of fabrication, as well as a variety of good mechanical behavior. The first part provides the introduction of some polymer-based materials used as biomaterials. The second part is more focused on silk fibroin applications as biomaterials that include silk fibroin structure, biocompatibility, degradation, immunological responses, sterilizability, drug delivery for osteogenesis, and fibroin reinforcement materials silk. © The Authors, published by EDP Sciences, 2018.
Dept. of Mechanical Engineering, Universitas Muhammadiyah Semarang, Semarang, 50273, Indonesia; Dept. of Mechanical Engineering, Brawijaya University, Malang, Malang, 65145, Indonesia; Dept. of Health Analyst, Universitas Muhammadiyah Semarang, Semarang, 50273, Indonesia
