Anugrah Robby Pratama, Danung Nur Adli, Mohammad Miftakhus Sholikin, Pradita Iustitia Sitaresmi
This review aimed to explore the role of Saccharomyces cerevisiae (S. cerevisiae) as a probiotic in poultry nutrition, with a focus on its effects on growth performance, gut health, immunity, and production parameters. The increasing demand for poultry products necessitates the development of sustainable strategies to increase productivity while maintaining animal health and ensuring food safety. The ban on antibiotic growth promoters (AGPs) due to concerns over antimicrobial resistance (AMR) has led to a search for viable alternatives, with probiotics emerging as promising candidates. Among these strains, Saccharomyces cerevisiae has gained attention for its multifaceted benefits in poultry nutrition. This study explored the role of S. cerevisiae as a probiotic, focusing on its effects on growth performance, gut health, immunity, and production parameters. Extensive research has shown that S. cerevisiae improves nutrient digestibility, enhances the gut microbiota balance, strengthens immune responses, and mitigates the effects of environmental stressors. In laying hens, S. cerevisiae supplementation has been associated with improved egg production and quality by optimizing nutrient absorption and calcium metabolism. However, inconsistencies in research findings, which are influenced by environmental conditions and supplementation protocols, necessitate further investigation. This review synthesizes current evidence on the application of S. cerevisiae in poultry diets, highlighting its potential as a sustainable alternative to antibiotics and providing insights into optimizing its use in antibiotic-free poultry farming. © 2026, Unique Scientific Publishers. All rights reserved.
Department of Animal Science, Faculty of Animal and Agricultural Sciences, Universitas Diponegoro, Central Java, Semarang, Indonesia; Department of Feed and Animal Nutrition, Smart Livestock Industry Study Programme, Faculty of Animal Science, Universitas Brawijaya, East Java, Malang, Indonesia; Research Center for Animal Husbandry, National Research and Innovation Agency (BRIN), Bogor, 16915, Indonesia
