Ahmad Afif Supianto, Rizky Nurdiansyah, Chia-Wei Weng, Heni Dwi Windarwati, Raden Sandra Yuwana, Andria Arisal, Vicky Zilvan, Hilman Ferdinandus Pardede, Chien-Hung Huang, Ana Heryana, Dikdik Krisnandi, Ka-Lok Ng
The world immediately studied Coronavirus Disease 2019 (COVID-19) and raced towards finding the cure and developing an effective treatment. An automated approach is needed to discover drug candidates and provide those data to facilitate clinical trials in saving time and only focusing on the candidates which potentially become the cure for COVID-19. We propose the Drug Candidates for the Prevention of COVID-19 (DCPC) Database. DCPC Database provides a list of candidates of potential drugs for the prevention of COVID-19 based on disease-drug associations which are automatically discovered from biomedical literature. DCPC database is an integrative structural database, which involves a chemical database repository, such as PubChem and DrugBank to ensure that drug compound candidates have a standard representation of compounds. The database provides keyword-chosen categories and a determination of minimum supported articles for search, a list of drug candidates in the sorted table followed by the detail for each candidate, and a download feature. The keyword category consists of three keywords, they are Chinese herbal compounds, Indian medicinal plants/and Indian medicinal plants & diabetic treatment herbs. Each candidate links to an article in the biomedical literature and to a page of the compound structure visualization. DCPC is freely available at https://dcpc.brin.go.id/dcpc/. © 2022 IEEE.
Research Center for Data and Information Sciences, National Research and Innovation Agency, Indonesia; Department of Bioinformatics, Indonesia International Institute for Life Sciences, Indonesia; Institute of Medicine, Chung Shan Medical University, Taiwan; Department of Mental Health Nursing, Faculty of Medicine, Universitas Brawijaya, Indonesia; Department of Computer Science and Information Engineering, National Formosa University, Taiwan; Department of Bioinformatics and Medical Engineering, Asia Universfty, Taiwan
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